How VANRAFIA® Works

Why VANRAFIA?
.
Just one pill once a day, with or without food
As an add-on to blood pressure medications like an ACEi or ARB
An IgAN therapy designed to target the ETA pathway
Not a steroid
Rapid and sustained reduction in proteinuria as early as Week 6 and sustained through Month 9
Reduction in proteinuria at 9 months:
38% with VANRAFIA + blood pressure medications vs 3% with placebo (sugar pill) + blood pressure medications*
*Participants were on a stable and maximally tolerated dose of a blood pressure medication, like ACEi or ARB. This study assessed urine protein levels using samples taken over 24 hours.
The most common adverse reactions (≥5%) with VANRAFIA were: swelling of hands, legs, ankles, and feet and low red blood cells.

DID YOU KNOW?
There’s a doctor conversation starter to help you talk to your doctor about VANRAFIA.


