How VANRAFIA® Works
Why VANRAFIA?
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Just one pill once a day, with or without food
As an add-on to blood pressure medications like an ACEi or ARB
An IgAN therapy designed to target the ETA pathway
Not a steroid
Rapid and sustained reduction in proteinuria as early as Week 6 and sustained through Month 9
Reduction in proteinuria at 9 months:
38% with VANRAFIA + blood pressure medications vs 3% with placebo (sugar pill) + blood pressure medications*
*Participants were on a stable and maximally tolerated dose of a blood pressure medication, like ACEi or ARB. This study assessed urine protein levels using samples taken over 24 hours.
The most common adverse reactions (≥5%) with VANRAFIA were: swelling of hands, legs, ankles, and feet and low red blood cells.
DID YOU KNOW?
There’s a doctor conversation starter to help you talk to your doctor about VANRAFIA.
Understanding IgAN and how VANRAFIA works
Activation of the ETA pathway is thought to contribute to IgAN
VANRAFIA is designed to target the ETA pathway
